TLR10, toll like receptor 10, 81793

N. diseases: 71; N. variants: 25
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs11466657
rs11466657 		0.925 0.120 4 38774173 missense variant A/G snv 2.7E-02; 4.0E-06 2.4E-02
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.010 1.000 1 2016 2016
dbSNP: rs11466657
rs11466657 		0.925 0.120 4 38774173 missense variant A/G snv 2.7E-02; 4.0E-06 2.4E-02
CUI: C0035435
Disease: Rheumatism
Rheumatism 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs11466657
rs11466657 		0.925 0.120 4 38774173 missense variant A/G snv 2.7E-02; 4.0E-06 2.4E-02
CUI: C0009326
Disease: Collagen Diseases
Collagen Diseases 		Skin and Connective Tissue Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs11466651
rs11466651 		0.925 0.120 4 38774699 missense variant C/T snv 6.5E-02 4.6E-02
CUI: C2607914
Disease: Allergic rhinitis (disorder)
Allergic rhinitis (disorder) 		Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases 0.010 1.000 1 2010 2010
dbSNP: rs4129009
rs4129009 		0.882 0.120 4 38773268 missense variant T/A;C;G snv 0.17 0.13
CUI: C0004096
Disease: Asthma
Asthma 		Respiratory Tract Diseases; Immune System Diseases 0.020 1.000 2 2017 2018
dbSNP: rs11466651
rs11466651 		0.925 0.120 4 38774699 missense variant C/T snv 6.5E-02 4.6E-02
CUI: C0004096
Disease: Asthma
Asthma 		Respiratory Tract Diseases; Immune System Diseases 0.010 1.000 1 2010 2010
dbSNP: rs28393318
rs28393318 		1.000 0.080 4 38782646 intron variant A/G snv 0.29
CUI: C0004096
Disease: Asthma
Asthma 		Respiratory Tract Diseases; Immune System Diseases 0.700 1.000 1 2018 2018
dbSNP: rs11096955
rs11096955 		0.851 0.200 4 38774486 missense variant T/C;G snv 4.3E-06; 0.41
CUI: C0018784
Disease: Sensorineural Hearing Loss (disorder)
Sensorineural Hearing Loss (disorder) 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases 0.010 1.000 1 2013 2013
dbSNP: rs4129009
rs4129009 		0.882 0.120 4 38773268 missense variant T/A;C;G snv 0.17 0.13
CUI: C0043144
Disease: Wheezing
Wheezing 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2016 2016
dbSNP: rs11096955
rs11096955 		0.851 0.200 4 38774486 missense variant T/C;G snv 4.3E-06; 0.41
CUI: C0025281
Disease: Meniere Disease
Meniere Disease 		Otorhinolaryngologic Diseases 0.010 1.000 1 2013 2013
dbSNP: rs11096955
rs11096955 		0.851 0.200 4 38774486 missense variant T/C;G snv 4.3E-06; 0.41
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2008 2008
dbSNP: rs11096955
rs11096955 		0.851 0.200 4 38774486 missense variant T/C;G snv 4.3E-06; 0.41
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2008 2008
dbSNP: rs11096957
rs11096957 		0.790 0.160 4 38774870 missense variant T/G snv 0.42 0.41
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2008 2008
dbSNP: rs11096957
rs11096957 		0.790 0.160 4 38774870 missense variant T/G snv 0.42 0.41
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2008 2008
dbSNP: rs866195758
rs866195758 		0.925 0.080 4 38774477 frameshift variant GCAGTTGGAT/- del
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2008 2008
dbSNP: rs866195758
rs866195758 		0.925 0.080 4 38774477 frameshift variant GCAGTTGGAT/- del
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2008 2008
dbSNP: rs11466653
rs11466653 		1.000 0.080 4 38774614 missense variant A/G snv 6.4E-02 4.1E-02
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2013 2013
dbSNP: rs11466653
rs11466653 		1.000 0.080 4 38774614 missense variant A/G snv 6.4E-02 4.1E-02
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2013 2013
dbSNP: rs4129009
rs4129009 		0.882 0.120 4 38773268 missense variant T/A;C;G snv 0.17 0.13
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs11096957
rs11096957 		0.790 0.160 4 38774870 missense variant T/G snv 0.42 0.41
CUI: C0409952
Disease: Idiopathic osteoarthritis
Idiopathic osteoarthritis 		Musculoskeletal Diseases 0.010 1.000 1 2018 2018
dbSNP: rs11096957
rs11096957 		0.790 0.160 4 38774870 missense variant T/G snv 0.42 0.41
CUI: C0263746
Disease: Osteoarthritis of the hand
Osteoarthritis of the hand 		Musculoskeletal Diseases 0.010 1.000 1 2018 2018
dbSNP: rs11096957
rs11096957 		0.790 0.160 4 38774870 missense variant T/G snv 0.42 0.41
CUI: C1384584
Disease: Generalized osteoarthritis
Generalized osteoarthritis 		Musculoskeletal Diseases 0.010 1.000 1 2018 2018
dbSNP: rs11096957
rs11096957 		0.790 0.160 4 38774870 missense variant T/G snv 0.42 0.41
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		Musculoskeletal Diseases 0.010 1.000 1 2018 2018
dbSNP: rs11466648
rs11466648 		0.925 0.040 4 38775321 synonymous variant T/C snv 7.0E-03 2.9E-02
CUI: C0410702
Disease: Adolescent idiopathic scoliosis
Adolescent idiopathic scoliosis 		Musculoskeletal Diseases 0.700 1.000 1 2018 2018
dbSNP: rs4129009
rs4129009 		0.882 0.120 4 38773268 missense variant T/A;C;G snv 0.17 0.13
CUI: C0006271
Disease: Bronchiolitis
Bronchiolitis 		Infections; Respiratory Tract Diseases 0.010 < 0.001 1 2016 2016